Medical LLMs

There is overwhelming evidence from both academic research and industry benchmarks that domain-specific, task-optimized large language models consistently outperform general-purpose LLMs in healthcare. At John Snow Labs, we’ve developed a suite of Medical LLMs purpose-built for clinical, biomedical, and life sciences applications.

Our models are designed to deliver best-in-class performance across a wide range of medical tasks—from clinical reasoning and diagnostics to medical research comprehension and genetic analysis.

Medical LLMs Offering

Model Name	Parameters	Recommended GPU Memory	Max Sequence Length	Model Size	Max KV-Cache	Tensor Parallel Sizes
Medical-LLM-7B	7B	~25 GB	16K	14 GB	11 GB	1, 2, 4
Medical-LLM-10B	10B	~35 GB	32K	19 GB	15 GB	1, 2, 4
Medical-LLM-14B	14B	~40 GB	16K	27 GB	13 GB	1, 2
Medical-LLM-24B	24B	~69 GB	32K	44 GB	25 GB	1, 2, 4, 8
Medical-LLM-Small	14B	~58 GB	32K	28 GB	30 GB	1, 2, 4, 8
Medical-LLM-Medium	70B	~452 GB	128K	131 GB	320 GB	4, 8
Medical-Reasoning-LLM-14B	14B	~58 GB	32K	28 GB	30 GB	1, 2, 4, 8
Medical-Reasoning-LLM-32B	32B	~222 GB	128K	61 GB	160 GB	2, 4, 8

Note: All memory calculations are based on half-precision (fp16/bf16) weights. Recommended GPU Memory considers the model size and the maximum key-value cache at the model’s maximum sequence length. These calculations follow the guidelines from DJL’s LMI Deployment Guide.

Introduction

John Snow Labs’ latest 2025 release of its Medical Large Language Models advance Healthcare AI by setting new state-of-the-art accuracy on medical LLM benchmarks. This advances what’s achievable in a variety of real-world use cases including clinical assessment, medical question answering, biomedical research synthesis, and diagnostic decision support.

Leading the pack is their largest 70B model, which can read and understand up to 32,000 words at once – that’s roughly 64 pages of medical text. The model is specially trained to work with medical information, from patient records to research papers, making it highly accurate for healthcare tasks. What makes this release special is how well the model performs while still being practical enough for everyday use in hospitals and clinics – thanks to a suite of models in different sizes, that balance accuracy with speed, cost, and privacy.

OpenMed Benchmark Performance

The comprehensive evaluation of John Snow Labs’ Medical LLM suite encompasses multiple standardized benchmarks, providing a thorough assessment of their capabilities across various medical domains. These evaluations demonstrate not only the models’ proficiency in medical knowledge but also their practical applicability in real-world healthcare scenarios.

The OpenMed evaluation framework represents one of the most rigorous testing environments for medical AI models, covering a broad spectrum of medical knowledge and clinical reasoning capabilities. Our models have undergone extensive testing across multiple categories, achieving remarkable results that validate their exceptional performance:

Model Performance Matrix

Large (70B+) Models Comparison

Smaller Models Comparison

All scores are presented as percentages (%)

Open Medical Leaderboard Performance Analysis

John Snow Labs’ Medical LLMs have been rigorously evaluated against leading general-purpose and medical-specific models, including GPT-4 and Med-PaLM-2. Here’s a detailed breakdown of their performance across key medical domains:

1. Clinical Knowledge

   • Outperforms GPT-4 in clinical knowledge assessment (89.43% vs 86.04%)

   • Shows stronger diagnostic and treatment planning capabilities

2. Medical Genetics

   • Exceeds both GPT-4 and Med-PaLM-2 in genetic analysis (95% vs 91% and 90%)

   • Demonstrates advanced understanding of genetic disorders and inheritance patterns

3. Medical Knowledge: Anatomy

   • Superior anatomical knowledge compared to both alternatives (85.19% vs 80% and 77.8%)

   • Shows stronger grasp of structural and functional relationships

4. Clinical Reasoning: Professional Practice

   • Surpasses GPT-4 in professional medical scenarios (94.85% vs 93.01%)

   • Better understanding of medical protocols and clinical guidelines

5. Cross-Domain Capability: Life Sciences

   • Slightly lower than GPT-4 but comparable to Med-PaLM-2 (93.75% vs 95.14% and 94.4%)

   • Strong foundation in biological sciences and medical principles

6. Medical Knowledge: Core Concepts

   • Significantly outperforms both models (83.24% vs 76.88% and 80.9%)

   • Better understanding of fundamental medical concepts

7. Clinical Case Analysis

   • Slightly better performance in clinical case scenarios (79.81% vs 78.87% and 79.7%)

   • More accurate in diagnostic decision-making

8. Medical Research Comprehension

   • Notable improvement over GPT-4 in research analysis (79.4% vs 75.2%)

   • Better at interpreting medical literature and research findings

9. Clinical Assessment

   • Substantially higher performance in clinical assessments (75.45% vs 69.52% and 71.3%)

   • Superior ability in evaluating clinical scenarios and treatment options

Small Yet Powerful: Efficiency Meets Performance

One of the standout features of John Snow Labs’ Medical LLMs is their efficiency at scale. These models deliver exceptional performance without requiring massive infrastructure:

• Designed to run efficiently on a range of GPU configurations

• Available in multiple sizes (7B, 10B, 14B, 24B, 70B) to suit different deployment needs

• Optimized for both on-premise and private cloud deployments

💡 You can achieve cutting-edge performance in clinical NLP without the costs and risks of using massive general-purpose models.

💡The figures demonstrate the comparative performance metrics of our models across key medical benchmarks and clinical reasoning tasks.

Medical-LLM – 14B

• Achieves 81.42% average score vs GPT-4’s 82.85% and Med-PaLM-2’s 84.08%
• Clinical knowledge score of 92.36% vs Med-PaLM-2’s 88.3%
• Medical reasoning at 90% matches Med-PaLM-2’s performance
• Higher accuracy than Meditron-70B while using 5x less parameters
• Suitable for deployment scenarios with compute constraints

Medical-LLM – 10B

• Average score of 75.19% across medical benchmarks
• Clinical analysis score of 88.19% vs Med-PaLM-1’s 83.8%
• Medical Genetics score of 82% vs Med-PaLM-1’s 75%
• Comparable performance to models requiring 7x more parameters
• Balanced option for resource-conscious implementations

Medical-LLM – 7B

• Clinical reasoning score of 86.81% vs Med-PaLM-1’s 83.8%
• Average score of 71.70% on OpenMed benchmark suite
• PubMedQA score of 75.6%, higher than other 7B models
• Matches GPT-4’s accuracy on medical QA with 100x fewer parameters
• Efficient choice for high-throughput clinical applications

Performance-to-Size Comparison

These models are available for on-premise deployment as well as through leading cloud marketplaces, making deployment and integration straightforward for healthcare organizations. The marketplace availability ensures scalable access to these state-of-the-art medical AI capabilities, with enterprise-grade security and compliance features built-in. Organizations can leverage these models through flexible consumption-based pricing models, enabling both small-scale implementations and large enterprise deployments.

Partner With Us

We’re committed to helping you stay at the cutting edge of medical AI. Whether you’re building decision support tools, clinical chatbots, or research platforms — our team is here to help.

 Book a call with our experts to: 

• Discuss your specific use case
• Get a live demo of the Medical LLMs
• Explore tailored deployment options.