Description
This model maps clinical terms to their corresponding MedDRA LLT (Lowest Level Term) codes using sbiobert_base_cased_mli Sentence Bert Embeddings. It also returns the MedDRA Preferred Term codes of each MedDRA LLT code in the all_k_aux_labels in the metadata.
Predicted Entities
How to use
documentAssembler = DocumentAssembler()\
.setInputCol("text")\
.setOutputCol("document")
sentenceDetector = SentenceDetectorDLModel.pretrained("sentence_detector_dl_healthcare","en","clinical/models")\
.setInputCols(["document"])\
.setOutputCol("sentence")
tokenizer = Tokenizer()\
.setInputCols(["sentence"])\
.setOutputCol("token")
word_embeddings = WordEmbeddingsModel.pretrained("embeddings_clinical","en", "clinical/models")\
.setInputCols(["sentence", "token"])\
.setOutputCol("embeddings")
ner_jsl = MedicalNerModel.pretrained("ner_jsl", "en", "clinical/models")\
.setInputCols(["sentence", "token", "embeddings"])\
.setOutputCol("ner_jsl")
ner_jsl_converter = NerConverter()\
.setInputCols(["sentence", "token", "ner_jsl"])\
.setOutputCol("ner_jsl_chunk")\
.setWhiteList(["Procedure","Kidney_Disease","Cerebrovascular_Disease","Heart_Disease",
"Disease_Syndrome_Disorder", "Symptom", "VS_Finding",
"EKG_Findings", "Communicable_Disease",
"Internal_organ_or_component","External_body_part_or_region",
"Triglycerides","Alcohol","Smoking","Pregnancy","Hypertension","Obesity",
"Injury_or_Poisoning","Test","Hyperlipidemia","Oncological",
"Psychological_Condition","LDL","Diabetes"])
ner_ade_clinical = MedicalNerModel.pretrained("ner_ade_clinical", "en", "clinical/models")\
.setInputCols(["sentence", "token", "embeddings"])\
.setOutputCol("ade_clinica_ner")
ner_ade_clinical_converter = NerConverterInternal()\
.setInputCols(["sentence", "token", "ade_clinica_ner"])\
.setOutputCol("ner_ade_clinical_chunk")\
.setWhiteList(["ADE"])
chunk_merger = ChunkMergeApproach()\
.setInputCols('ner_ade_clinical_chunk',"ner_jsl_chunk")\
.setOutputCol('merged_ner_chunk')
chunk2doc = Chunk2Doc() \
.setInputCols("merged_ner_chunk") \
.setOutputCol("ner_chunk_doc")
sbert_embedder = BertSentenceEmbeddings.pretrained("sbiobert_base_cased_mli","en","clinical/models")\
.setInputCols(["ner_chunk_doc"])\
.setOutputCol("sbert_embeddings")\
.setCaseSensitive(False)
meddra_resolver = SentenceEntityResolverModel.load("sbiobertresolve_meddra_lowest_level_term") \
.setInputCols(["sbert_embeddings"]) \
.setOutputCol("meddra_llt_code")\
.setDistanceFunction("EUCLIDEAN")
nlpPipeline= Pipeline(stages=[
documentAssembler,
sentenceDetector,
tokenizer,
word_embeddings,
ner_jsl,
ner_jsl_converter,
chunk2doc,
sbert_embedder,
meddra_resolver
])
text= """This is an 82-year-old male with a history of prior tobacco use, benign hypertension, chronic renal insufficiency, chronic bronchitis, gastritis, and ischemic attack. He initially presented to Braintree with ST elevation and was transferred to St. Margaret’s Center. He underwent cardiac catheterization because of the left main coronary artery stenosis, which was complicated by hypotension and bradycardia. We describe the side effects of 5-FU in a colon cancer patient who suffered mucositis and dermatitis."""
df= spark.createDataFrame([[text]]).toDF("text")
resolver_pipeline= nlpPipeline.fit(df)
result = resolver_pipeline.transform(df)
val documentAssembler = new DocumentAssembler()
.setInputCol("text")
.setOutputCol("document")
val sentenceDetector = SentenceDetectorDLModel.pretrained("sentence_detector_dl_healthcare","en","clinical/models")
.setInputCols(Array("document"))
.setOutputCol("sentence")
val tokenizer = new Tokenizer()
.setInputCols(Array("sentence"))
.setOutputCol("token")
val word_embeddings = WordEmbeddingsModel.pretrained("embeddings_clinical","en","clinical/models")
.setInputCols(Array("sentence","token"))
.setOutputCol("embeddings")
val ner_jsl = MedicalNerModel.pretrained("ner_jsl","en","clinical/models")
.setInputCols(Array("sentence","token","embeddings"))
.setOutputCol("ner_jsl")
val ner_jsl_converter = new NerConverter()
.setInputCols(Array("sentence","token","ner_jsl"))
.setOutputCol("ner_jsl_chunk")
.setWhiteList(Array("Procedure","Kidney_Disease","Cerebrovascular_Disease","Heart_Disease", "Disease_Syndrome_Disorder","Symptom","VS_Finding", "EKG_Findings","Communicable_Disease", "Internal_organ_or_component","External_body_part_or_region", "Triglycerides","Alcohol","Smoking","Pregnancy","Hypertension","Obesity", "Injury_or_Poisoning","Test","Hyperlipidemia","Oncological", "Psychological_Condition","LDL","Diabetes"))
val ner_ade_clinical = MedicalNerModel.pretrained("ner_ade_clinical","en","clinical/models")
.setInputCols(Array("sentence","token","embeddings"))
.setOutputCol("ade_clinica_ner")
val ner_ade_clinical_converter = new NerConverterInternal()
.setInputCols(Array("sentence","token","ade_clinica_ner"))
.setOutputCol("ner_ade_clinical_chunk")
.setWhiteList(Array("ADE"))
val chunk_merger = new ChunkMergeApproach()
.setInputCols("ner_ade_clinical_chunk","ner_jsl_chunk")
.setOutputCol("merged_ner_chunk")
val chunk2doc = new Chunk2Doc()
.setInputCols("merged_ner_chunk")
.setOutputCol("ner_chunk_doc")
val sbert_embedder = BertSentenceEmbeddings.pretrained("sbiobert_base_cased_mli","en","clinical/models")
.setInputCols(Array("ner_chunk_doc"))
.setOutputCol("sbert_embeddings")
.setCaseSensitive(false)
val meddra_resolver = new SentenceEntityResolverModel.load("sbiobertresolve_meddra_lowest_level_term")
.setInputCols(Array("sbert_embeddings"))
.setOutputCol("meddra_llt_code")
.setDistanceFunction("EUCLIDEAN")
nlpPipeline= new Pipeline().setStages(Array( documentAssembler,
sentenceDetector,
tokenizer,
word_embeddings,
ner_jsl,
ner_jsl_converter,
ner_ade_clinical,
ner_ade_clinical_converter,
chunk_merger,
chunk2doc,
sbert_embedder,
meddra_resolver))
text= """This is an 82-year-old male with a history of prior tobacco use,benign hypertension,chronic renal insufficiency,chronic bronchitis,gastritis,and ischemic attack. He initially presented to Braintree with ST elevation and was transferred to St. Margaret’s Center. He underwent cardiac catheterization because of the left main coronary artery stenosis,which was complicated by hypotension and bradycardia. We describe the side effects of 5-FU in a colon cancer patient who suffered mucositis and dermatitis."""
df= Seq(text).toDF("text")
resolver_pipeline= nlpPipeline.fit(df)
val result = resolver_pipeline.transform(df)
Results
+----------------------------------+-----+---+-------------------------+---------------+----------------------------------+------------------------------------------------------------+------------------------------------------------------------+
| ner_chunk|begin|end| entity|meddra_llt_code| resolution| all_k_results| all_k_resolutions|
+----------------------------------+-----+---+-------------------------+---------------+----------------------------------+------------------------------------------------------------+------------------------------------------------------------+
| tobacco| 52| 58| Smoking| 10067622| tobacco interaction|10067622:::10086359:::10057581:::10082288:::10009180:::10...|tobacco interaction:::tobaccoism:::tobacco user:::exposur...|
| hypertension| 72| 83| Hypertension| 10020772| hypertension|10020772:::10020790:::10088636:::10081425:::10015488:::10...|hypertension:::hypertension secondary:::systemic hyperten...|
| chronic renal insufficiency| 86|112| Kidney_Disease| 10050441| chronic renal insufficiency|10050441:::10009122:::10009119:::10075441:::10038474:::10...|chronic renal insufficiency:::chronic renal impairment:::...|
| bronchitis| 123|132|Disease_Syndrome_Disorder| 10006451| bronchitis|10006451:::10006448:::10008841:::10085668:::10061736:::10...|bronchitis:::bronchiolitis:::chronic bronchitis:::capilla...|
| gastritis| 135|143|Disease_Syndrome_Disorder| 10017853| gastritis|10017853:::10060703:::10076492:::10070814:::10088553:::10...|gastritis:::verrucous gastritis:::antral gastritis:::corr...|
| ischemic attack| 150|164| Cerebrovascular_Disease| 10072760| transient ischemic attack|10072760:::10060848:::10060772:::10061216:::10055221:::10...|transient ischemic attack:::ischemic cerebral infarction:...|
| cardiac catheterization| 280|302| Procedure| 10048606| cardiac catheterization|10048606:::10007527:::10054343:::10007815:::10053451:::10...|cardiac catheterization:::cardiac catheterisation:::cathe...|
|left main coronary artery stenosis| 319|352| Heart_Disease| 10090240|left main coronary artery stenosis|10090240:::10072048:::10084343:::10011089:::10083430:::10...|left main coronary artery stenosis:::left anterior descen...|
| hypotension| 380|390| VS_Finding| 10021097| hypotension|10021097:::10021107:::10066331:::10066077:::10036433:::10...|hypotension:::hypotensive:::arterial hypotension:::diasto...|
| bradycardia| 396|406| VS_Finding| 10006093| bradycardia|10006093:::10040741:::10078310:::10064883:::10065585:::10...|bradycardia:::sinus bradycardia:::central bradycardia:::r...|
| colon cancer| 451|462| Oncological| 10009944| colon cancer|10009944:::10009989:::10009957:::10061451:::10007330:::10...|colon cancer:::colonic cancer:::colon carcinoma:::colorec...|
| mucositis| 485|493| ADE| 10028127| mucositis|10028127:::10065880:::10065900:::10006525:::10021960:::10...|mucositis:::laryngeal mucositis:::tracheal mucositis:::bu...|
| dermatitis| 499|508| ADE| 10012431| dermatitis|10012431:::10048768:::10003639:::10012470:::10073737:::10...|dermatitis:::dermatosis:::atopic dermatitis:::dermatitis ...|
+----------------------------------+-----+---+-------------------------+---------------+----------------------------------+------------------------------------------------------------+------------------------------------------------------------+
Model Information
| Model Name: | sbiobertresolve_meddra_lowest_level_term |
| Compatibility: | Healthcare NLP 5.3.0+ |
| License: | Licensed |
| Edition: | Official |
| Input Labels: | [sentence_embeddings] |
| Output Labels: | [meddra_llt_code] |
| Language: | en |
| Size: | 228.2 MB |
| Case sensitive: | false |
References
This model is trained with the January 2024 (v27) release of ICD-10 to MedDRA Map dataset.
To utilize this model, possession of a valid MedDRA license is requisite. If you possess one and wish to use this model, kindly contact us at support@johnsnowlabs.com.