Detect Adverse Drug Events (clinical_large)

Description

Detect adverse reactions to drugs in reviews, tweets, and medical text using a pre-trained NER model.

Predicted Entities

DRUG, ADE

Live Demo Open in Colab Copy S3 URI

How to use

document_assembler = DocumentAssembler()\
    .setInputCol("text")\
    .setOutputCol("document")

sentence_detector = SentenceDetectorDLModel.pretrained("sentence_detector_dl", "en")\
    .setInputCols(["document"])\
    .setOutputCol("sentence")

tokenizer = Tokenizer()\
    .setInputCols(["sentence"])\
    .setOutputCol("token")

clinical_embeddings = WordEmbeddingsModel.pretrained("embeddings_clinical_large", "en", "clinical/models")\
    .setInputCols(["sentence", "token"])\
    .setOutputCol("embeddings")

ner_model = MedicalNerModel.pretrained("ner_ade_emb_clinical_large", "en", "clinical/models")\
    .setInputCols(["sentence", "token","embeddings"])\
    .setOutputCol("ner")

ner_converter = NerConverterInternal()\
    .setInputCols(['sentence', 'token', 'ner'])\
    .setOutputCol('ner_chunk')

pipeline = Pipeline(stages=[
    document_assembler, 
    sentence_detector,
    tokenizer,
    clinical_embeddings,
    ner_model,
    ner_converter   
    ])

sample_df = spark.createDataFrame([["Been taking Lipitor for 15 years , have experienced severe fatigue a lot!!! . Doctor moved me to voltaren 2 months ago , so far , have only experienced cramps."]]).toDF("text")

result = pipeline.fit(sample_df).transform(sample_df)
val document_assembler = new DocumentAssembler()
    .setInputCol("text")
    .setOutputCol("document")

val sentence_detector = SentenceDetectorDLModel.pretrained("sentence_detector_dl", "en")
    .setInputCols("document")
    .setOutputCol("sentence")

val tokenizer = new Tokenizer()
    .setInputCols("sentence")
    .setOutputCol("token")

val clinical_embeddings = WordEmbeddingsModel.pretrained("embeddings_clinical_large", "en", "clinical/models")
    .setInputCols(Array("sentence", "token"))
    .setOutputCol("embeddings")

val ner_model = MedicalNerModel.pretrained("ner_ade_emb_clinical_large", "en", "clinical/models")
    .setInputCols(Array("sentence", "token", "embeddings"))
    .setOutputCol("ner")

val ner_converter = new NerConverterInternal()
    .setInputCols(Array("sentence", "token", "ner"))
    .setOutputCol("ner_chunk")

val pipeline = new Pipeline().setStages(Array(
    document_assembler, 
    sentence_detector,
    tokenizer,
    clinical_embeddings,
    ner_model,
    ner_converter))

val sample_data = Seq("Been taking Lipitor for 15 years , have experienced severe fatigue a lot!!! . Doctor moved me to voltaren 2 months ago , so far , have only experienced cramps.").toDS.toDF("text")

val result = pipeline.fit(sample_data).transform(sample_data)

Results

+--------------+-----+---+---------+
|chunk         |begin|end|ner_label|
+--------------+-----+---+---------+
|Lipitor       |12   |18 |DRUG     |
|severe fatigue|52   |65 |ADE      |
|voltaren      |97   |104|DRUG     |
|cramps        |152  |157|ADE      |
+--------------+-----+---+---------+

Model Information

Model Name: ner_ade_emb_clinical_large
Compatibility: Healthcare NLP 4.4.2+
License: Licensed
Edition: Official
Input Labels: [sentence, token, embeddings]
Output Labels: [ner]
Language: en
Size: 2.7 MB

Benchmarking

       label  precision    recall  f1-score   support
        DRUG       0.92      0.91      0.92     16032
         ADE       0.82      0.80      0.81      6142
   micro-avg       0.89      0.88      0.89     22174
   macro-avg       0.87      0.86      0.86     22174
weighted-avg       0.89      0.88      0.89     22174