Description
Extract relations to fully understand the origin of some phenotypic abnormalities and their associated diseases. 1 : Entities are related, 0 : Entities are not related.
Predicted Entities
0, 1
How to use
...
documenter = DocumentAssembler()\
.setInputCol("text")\
.setOutputCol("document")
sentencer = SentenceDetector()\
.setInputCols(["document"])\
.setOutputCol("sentences")
tokenizer = sparknlp.annotators.Tokenizer()\
.setInputCols(["sentences"])\
.setOutputCol("tokens")
pos_tagger = PerceptronModel()\
.pretrained("pos_clinical", "en", "clinical/models") \
.setInputCols(["sentences", "tokens"])\
.setOutputCol("pos_tags")
words_embedder = WordEmbeddingsModel() \
.pretrained("embeddings_clinical", "en", "clinical/models") \
.setInputCols(["sentences", "tokens"]) \
.setOutputCol("embeddings")
ner_tagger = MedicalNerModel.pretrained("ner_human_phenotype_gene_clinical", "en", "clinical/models")\
.setInputCols("sentences", "tokens", "embeddings")\
.setOutputCol("ner_tags")
ner_converter = NerConverter() \
.setInputCols(["sentences", "tokens", "ner_tags"]) \
.setOutputCol("ner_chunks")
dependency_parser = DependencyParserModel() \
.pretrained("dependency_conllu", "en") \
.setInputCols(["sentences", "pos_tags", "tokens"]) \
.setOutputCol("dependencies")
#Set a filter on pairs of named entities which will be treated as relation candidates
re_ner_chunk_filter = RENerChunksFilter() \
.setInputCols(["ner_chunks", "dependencies"])\
.setMaxSyntacticDistance(10)\
.setOutputCol("re_ner_chunks")
# The dataset this model is trained to is sentence-wise.
# This model can also be trained on document-level relations - in which case, while predicting, use "document" instead of "sentence" as input.
re_model = RelationExtractionDLModel()\
.pretrained('redl_human_phenotype_gene_biobert', 'en', "clinical/models") \
.setPredictionThreshold(0.5)\
.setInputCols(["re_ner_chunks", "sentences"]) \
.setOutputCol("relations")
pipeline = Pipeline(stages=[documenter, sentencer, tokenizer, pos_tagger, words_embedder, ner_tagger, ner_converter, dependency_parser, re_ner_chunk_filter, re_model])
text = """She has a retinal degeneration, hearing loss and renal failure, short stature, Mutations in the SH3PXD2B gene coding for the Tks4 protein are responsible for the autosomal recessive."""
data = spark.createDataFrame([[text]]).toDF("text")
p_model = pipeline.fit(data)
result = p_model.transform(data)
val documenter = new DocumentAssembler()
.setInputCol("text")
.setOutputCol("document")
val sentencer = new SentenceDetector()
.setInputCols("document")
.setOutputCol("sentences")
val tokenizer = new Tokenizer()
.setInputCols("sentences")
.setOutputCol("tokens")
val pos_tagger = PerceptronModel()
.pretrained("pos_clinical", "en", "clinical/models")
.setInputCols(Array("sentences", "tokens"))
.setOutputCol("pos_tags")
val words_embedder = WordEmbeddingsModel()
.pretrained("embeddings_clinical", "en", "clinical/models")
.setInputCols(Array("sentences", "tokens"))
.setOutputCol("embeddings")
val ner_tagger = MedicalNerModel.pretrained("ner_human_phenotype_gene_clinical", "en", "clinical/models")
.setInputCols(Array("sentences", "tokens", "embeddings"))
.setOutputCol("ner_tags")
val ner_converter = new NerConverter()
.setInputCols(Array("sentences", "tokens", "ner_tags"))
.setOutputCol("ner_chunks")
val dependency_parser = DependencyParserModel()
.pretrained("dependency_conllu", "en")
.setInputCols(Array("sentences", "pos_tags", "tokens"))
.setOutputCol("dependencies")
// Set a filter on pairs of named entities which will be treated as relation candidates
val re_ner_chunk_filter = RENerChunksFilter()
.setInputCols(Array("ner_chunks", "dependencies"))
.setMaxSyntacticDistance(10)
.setOutputCol("re_ner_chunks")
// The dataset this model is trained to is sentence-wise.
// This model can also be trained on document-level relations - in which case, while predicting, use "document" instead of "sentence" as input.
val re_model = RelationExtractionDLModel()
.pretrained("redl_human_phenotype_gene_biobert", "en", "clinical/models")
.setPredictionThreshold(0.5)
.setInputCols(Array("re_ner_chunks", "sentences"))
.setOutputCol("relations")
val pipeline = new Pipeline().setStages(Array(documenter, sentencer, tokenizer, pos_tagger, words_embedder, ner_tagger, ner_converter, dependency_parser, re_ner_chunk_filter, re_model))
val data = Seq("""She has a retinal degeneration, hearing loss and renal failure, short stature, Mutations in the SH3PXD2B gene coding for the Tks4 protein are responsible for the autosomal recessive.""").toDS.toDF("text")
val result = pipeline.fit(data).transform(data)
import nlu
nlu.load("en.relation.humen_phenotype_gene").predict("""She has a retinal degeneration, hearing loss and renal failure, short stature, Mutations in the SH3PXD2B gene coding for the Tks4 protein are responsible for the autosomal recessive.""")
Results
| | relation | entity1 | entity1_begin | entity1_end | chunk1 | entity2 | entity2_begin | entity2_end | chunk2 | confidence |
|---:|-----------:|:----------|----------------:|--------------:|:---------------------|:----------|----------------:|--------------:|:--------------------|-------------:|
| 0 | 0 | HP | 10 | 29 | retinal degeneration | HP | 32 | 43 | hearing loss | 0.893809 |
| 1 | 0 | HP | 10 | 29 | retinal degeneration | HP | 49 | 61 | renal failure | 0.958486 |
| 2 | 1 | HP | 10 | 29 | retinal degeneration | HP | 162 | 180 | autosomal recessive | 0.65584 |
| 3 | 0 | HP | 32 | 43 | hearing loss | HP | 64 | 76 | short stature | 0.707055 |
| 4 | 1 | HP | 32 | 43 | hearing loss | GENE | 96 | 103 | SH3PXD2B | 0.640802 |
Model Information
| Model Name: | redl_human_phenotype_gene_biobert |
| Compatibility: | Healthcare NLP 3.0.3+ |
| License: | Licensed |
| Edition: | Official |
| Language: | en |
| Case sensitive: | true |
Data Source
Trained on a silver standard corpus of human phenotype and gene annotations and their relations.
Benchmarking
Relation Recall Precision F1 Support
0 0.922 0.908 0.915 129
1 0.831 0.855 0.843 71
Avg. 0.877 0.882 0.879 -